Pathway Background and Objectives
Community-Acquired Pneumonia (CAP) is among the most common causes for hospitalization and is responsible for 124,000 hospitalizations annually. In 2011, the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America released a clinical practice guideline with evidence-based recommendations for the management of CAP in infants and children. Since then, there has been a significant amount of literature clarifying CAP etiology, management and appropriate duration of treatment, in tandem with increasing susceptibility rates of S. pneumoniae to amoxicillin/ampicillin. The CAP clinical pathway was updated in 2023 to emphasize the selection of the narrowest appropriate antibiotic depending on the presence or absence of CAP complications (rather than the severity of the patient’s overall clinical presentation), decrease the utilization of azithromycin (as it has no significant clinical benefit for mycoplasma-associated uncomplicated CAP), and recommend a shorter duration of antibiotics.
The objectives of this pathway are to:
- Decrease variation in antibiotic usage
- Decrease unnecessary use of broad spectrum antibiotics
- Decrease unnecessary use of azithromycin
- Optimize ampicillin/amoxicillin dosing for local pneumococcal resistance
- Decrease antibiotic usage to shortest effective duration